PENG9580 Advanced Topics in Biomedical Engineering Course description

After completing the course, the student is expected to have achieved the following learning outcomes defined in terms of knowledge, skills and general competence:

Knowledge

The student

• can describe the structure of the human genome and different types of inheritance
• can describe different forms of genetic variation and their significance
• can explain gene regulation
• can explain the significance of DNA damage, how it can occur and how it can be repaired
• is familiar with the use of tumor markers and other biomarkers in patient diagnostics and individually adapted medicine
• can describe the principles behind the most common analysis methods in molecular diagnostics and explaining the methods’ areas of use
• is familiar with different forms of non-invasive prenatal testing (NIPT)
• can describe how DNA analyses can be used for personal identification in forensic medicine
• can describe different sequencing technologies and their areas of use
• can explain how chromosome anomalies and hereditary diseases can be determined by using different methods
• is familiar with the laws and regulations that regulate genetic testing and the requirements relating to genetic counselling
• is familiar with methods and laws relating to sperm donation, egg donation and in vitro fertilisation

Skills

The student

• can conduct and quality assure different gene technology methods and assess any sources of errors related to these
• can apply analysis instruments used in molecular diagnostics
• can process data and interpret the results of different genetic/DNS analyses, both technical and biomedical
• can carry out bioinformatics analyses of sequencing data from different sequencing platforms
• can collect information from different databases and using basic bioinformatics tools
• can carry out work using gene technology methods in a responsible manner to minimise the risk of contamination

General competence

The student

• can discuss social and ethical consequences of gene testing in a medical perspective

In order to be permitted to take the exam, the following must have been approved:

• a minimum of 90 per cent attendance in laboratory teaching
• laboratory reports in accordance with specified criteria

Supervised individual written exam, 4 hours

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All exam papers are assessed by two examiners. A minimum of twenty per cent of the exam papers will be assessed by an external examiner. The external examiner’s assessment shall benefit all students

The course consists of the following subject areas, specified below as the number of credits:

• Genetics and Molecular Diagnostics, 10 credits

10 credits overlap with BIO3200 Molecular Genetics

A panel of all presenters in the course, and at least one external representative will evaluate the report and the presentation.