MARAD5900 Master’s Thesis Course description

The master’s thesis must be an independent and supervised research or development work.

The students choose their own thesis topics. Students can initiate theses based on their own academic background and interests. Theses relating to research projects at OsloMet or external Norwegian and foreign partner institutions may also be relevant.

• Specialisation in radiography (part-time): The student must have passed all courses in the first year of study and the autumn semester in the second year before starting on the master’s thesis
• Specialisation in radiography with special admission (part-time): The student must have passed the courses HETEK4000 and HETEK4100 before starting on the master’s thesis

Emnet omhandler teoretiske og praktiske aspekter ved moderne DNA-teknologi anvendt for å detektere genetisk variasjon i det humane genomet (DNA) inkludert NGS metoder og analyse av NGS data. Det gir kunnskap om både normalvariasjon og variasjon knyttet til sykdomsdisposisjon. Laboratoriedelen omfatter praktisk innføring i PCR-metodikk, DNA-sekvensanalyse, DNA-fragmentanalyse og kvantitativ PCR (qPCR, analyse av genekspresjon). Den praktiske delen inkluderer også øvelser med basale bioinformatikkverktøy (f.eks. BLAST) for analyse av DNA- og RNA-sekvensdata. Studentene blir også introdusert til viktige databaser som GenBank.

Studenten må være tatt opp på Masterstudium i helse og teknologi - spesialisering i biomedisin. Emnet tilbys også som enkeltemne, forutsatt ledig plass. Opptakskrav til enkeltemnet er det samme som for spesialisering i biomedisin.

The following must have been approved in order for the student to take the exam:

• two oral presentations (up to 30 minutes) at the master’s seminars
• project outline with a progress schedule in accordance with specified criteria

If the seminars are taught in English, presentations must be given in English.

Written master’s thesis, individually or in groups of two students, followed by an individual oral exam including a presentation of the thesis, with a duration of up to 1.5 hours.

The master’s thesis can be written as a monograph of up to 80 pages or an article manuscript with a supplementary introductory chapter of up to 45 pages.

The written thesis must be awarded a grade of A-E (preliminary grade) in order for a student to take the oral exam. The final grade is set after the oral exam. The grade can be adjusted up or down by one grade based on the oral exam.

The thesis can be written in English or a Scandinavian language. The oral exam can be taken in English or a Scandinavian language, regardless of which language the thesis was written in.

Resit exam: If the master’s thesis is awarded an F (Fail), the student(s) will be given one (1) opportunity to submit a reworked version.

Students can appeal against the grade set for the written part of the exam. If the grade is changed after an appeal against the grade, and the oral exam has already been held, the oral exam must be retaken.

All aids are permitted, as long as the rules for source referencing are complied with.

Individuell skriftlig eksamen under tilsyn, 4 timer

Besvarelsen kan gis på engelsk eller et skandinavisk språk.

Håndholdt kalkulator som ikke kommuniserer trådløst og som ikke kan regne symbolsk. Dersom kalkulatoren har mulighet for lagring i internminnet skal minnet være slettet før eksamen. Stikkprøver kan foretas.