MABIO4710 Advanced Bioanalytical Methods Course description

No requirements over and above the admission requirements.

Analytical chemistry/bioanalysis at bachelor’s level.

Lectures and individual exercises. The exercises are based on the students’ own work, supervised by the lecturer and/or a student assistant.

After completing the course, the student should have the following learning outcomes defined in terms of knowledge, skills and general competence:

Knowledge

The student

• can explain the principles behind targeted and non-targeted analytical strategies in bioanalysis
• can describe advanced techniques for preparing biological matrices, including extraction and concentration techniques suitable for biological samples
• can describe the operation and applications of advanced analytical instruments, with emphasis on chromatographic and mass spectrometric techniques
• can explain quantitative analyses and calibration procedures used in bioanalysis, including the use of isotope-labelled standards, control samples and certified reference materials
• can explain procedures for identifying biomarkers, including data extraction, data processing and analysis of large amounts of analytical data
• can describe the principles for method development and validation in bioanalysis and the quality requirements that apply to such analyses

Skills

The student

• can make use of relevant literature as a basis for method development in bioanalysis
• can design proposals for analytical methods where independent choices of appropriate sample preparation and instrumental techniques need to be made
• can make use of different calibration techniques and associated quality control measures in quantitative analyses
• can perform biomarker identification based on chromatographic and mass spectrometric analyses
• can use statistical methods and statistical software to interpret and quality-test analysis results

General competence

The student

• can participate in quality assurance work and method development in the bioanalytical laboratory
• can contribute to the development of technology in the field
• has an overview of technology development and future perspectives in the field
• has insight into the applications and limitations of chromatographic and mass spectroscopic analytical techniques used in bioanalysis.

Individual written exam, 3 hours

The exam result can be appealed.

A handheld calculator that cannot be used for wireless communication or to perform symbolic calculations. If the calculator’s internal memory can store data, the memory must be deleted before the exam. Random checks may be carried out.

Grade scale A-F.

One internal examiner. External examiners are used regularly.

Emnet er ekvivalent (overlapper 10 studiepoeng) med: ITPE1300, FO019A og FO019I.

Ved praktisering av 3-gangers regelen for oppmelding til eksamen teller forsøk brukt i ekvivalente emner.

All papers will be assessed by two examiners, one of whom must be external.

None.