EPN-V2

MABIO4710 Advanced Bioanalytical Methods Course description

Course name in Norwegian
Avanserte bioanalytiske metoder
Study programme
Master´s Programme in Health and Technology - Specialisation in Biomedicine, elective modules
Master´s Programme in Health and Technology - Specialisation in Biomedicine
Master´s Programme in Pharmacy
Weight
10.0 ECTS
Year of study
2023/2024
Curriculum
SPRING 2024
Schedule
Course history

Introduction

No requirements over and above the admission requirements.

Recommended preliminary courses

Analytical chemistry/bioanalysis at bachelor’s level.

Required preliminary courses

Lectures and individual exercises. The exercises are based on the students’ own work, supervised by the lecturer and/or a student assistant.

Learning outcomes

After completing the course, the student should have the following learning outcomes defined in terms of knowledge, skills and general competence:

Knowledge

The student

  • can explain the principles behind targeted and non-targeted analytical strategies in bioanalysis
  • can describe advanced techniques for preparing biological matrices, including extraction and concentration techniques suitable for biological samples
  • can describe the operation and applications of advanced analytical instruments, with emphasis on chromatographic and mass spectrometric techniques
  • can explain quantitative analyses and calibration procedures used in bioanalysis, including the use of isotope-labelled standards, control samples and certified reference materials
  • can explain procedures for identifying biomarkers, including data extraction, data processing and analysis of large amounts of analytical data
  • can describe the principles for method development and validation in bioanalysis and the quality requirements that apply to such analyses

Skills

The student

  • can make use of relevant literature as a basis for method development in bioanalysis
  • can design proposals for analytical methods where independent choices of appropriate sample preparation and instrumental techniques need to be made
  • can make use of different calibration techniques and associated quality control measures in quantitative analyses
  • can perform biomarker identification based on chromatographic and mass spectrometric analyses
  • can use statistical methods and statistical software to interpret and quality-test analysis results

General competence

The student

  • can participate in quality assurance work and method development in the bioanalytical laboratory
  • can contribute to the development of technology in the field
  • has an overview of technology development and future perspectives in the field
  • has insight into the applications and limitations of chromatographic and mass spectroscopic analytical techniques used in bioanalysis.

Teaching and learning methods

Individual written exam, 3 hours

The exam result can be appealed.

Course requirements

A handheld calculator that cannot be used for wireless communication or to perform symbolic calculations. If the calculator’s internal memory can store data, the memory must be deleted before the exam. Random checks may be carried out.

Assessment

Grade scale A-F.

Permitted exam materials and equipment

One internal examiner. External examiners are used regularly.

Grading scale

Emnet er ekvivalent (overlapper 10 studiepoeng) med: ITPE1300, FO019A og FO019I.

Ved praktisering av 3-gangers regelen for oppmelding til eksamen teller forsøk brukt i ekvivalente emner.

Examiners

All papers will be assessed by two examiners, one of whom must be external.

Admission requirements

The course is offered as an individual course if there are vacant places. Admission requirements:

  • Bachelor’s degree or equivalent degree in medical laboratory sciences, pharmacy, biotechnology, chemical engineering or molecular biology.

Overlapping courses

None.