BIOB3200 Genetics and Molecular Diagnostics Course description

Etter fullført emne har studenten følgende læringsutbytte definert i kunnskap, ferdigheter og generell kompetanse:

Kunnskap

Studenten har

• kunnskap om vitenskapsteori, forskningsetikk og forskningsmetode
• bred kunnskap om nyere forskning innen bacheloroppgavens ergoterapifaglige tema

Ferdigheter

Studenten kan

• utarbeide en problemstilling og prosjektplan
• utarbeide abstrakt og bacheloroppgave basert på tradisjoner innen forskningsformidling
• anvende en relevant vitenskapelig metode og gjennomføre datainnsamling og analyse
• innhente, anvende og diskutere relevante forskningsartikler og annen faglitteratur fra nasjonalt og internasjonalt FoU-arbeid innen valgt tema
• diskutere, vurdere og reflektere over resultater og det som har påvirket resultatenes pålitelighet og gyldighet

Generell kompetanse

Studenten kan

• planlegge og gjennomføre relevante prosjekter med komplekse oppgaver som strekker seg over tid og som bidrar til utvikling av teori og/eller praksis i samarbeid med andre
• kritisk reflektere over forskningsetiske spørsmål og retningslinjer
• skriftlig formidle, diskutere og presentere resultater fra eget prosjekt

Bacheloroppgaven skal være et selvstendig faglig arbeid og skrives i grupper på to studenter. Den kan være et frittstående arbeid eller inngå som en avgrenset, men selvstendig del av et pågående forskningsprosjekt knyttet til interne eller eksterne miljøer. Studentene får tildelt veileder som følger gruppene i hele prosessen. Veiledningen er organisert med rundbords-veiledning der flere grupper jobber sammen, samt ordinær gruppeveiledning. Det gis inntil 5 timer veiledning per gruppe.

After completing the course, the student is expected to have achieved the following learning outcomes defined in terms of knowledge, skills and general competence: 

Knowledge 

The student

• can describe the structure of the human genome and different types of inheritance
• can describe different forms of genetic variation and their significance
• can explain gene regulation
• can explain the significance of DNA damage, how it can occur and how it can be repaired
• is familiar with the use of tumor markers and other biomarkers in patient diagnostics and individually adapted medicine
• can describe the principles behind the most common analysis methods in molecular diagnostics and explaining the methods’ areas of use
• is familiar with different forms of non-invasive prenatal testing (NIPT)
• can describe how DNA analyses can be used for personal identification in forensic medicine
• can describe different sequencing technologies and their areas of use
• can explain how chromosome anomalies and hereditary diseases can be determined by using different methods
• is familiar with the laws and regulations that regulate genetic testing and the requirements relating to genetic counselling
• is familiar with methods and laws relating to sperm donation, egg donation and in vitro fertilisation

Skills 

The student

• can conduct and quality assure different gene technology methods and assess any sources of errors related to these
• can apply analysis instruments used in molecular diagnostics
• can process data and interpret the results of different genetic/DNS analyses, both technical and biomedical
• can carry out bioinformatics analyses of sequencing data from different sequencing platforms
• can collect information from different databases and using basic bioinformatics tools
• can carry out work using gene technology methods in a responsible manner to minimise the risk of contamination

General competence

The student

• can discuss social and ethical consequences of gene testing in a medical perspective

Work and teaching methods include lectures, assignments, literature searches and laboratory work. The course entails a half-day’s practical training visit to an external laboratory. 

Parts of the teaching used is the ‘flipped classroom’, where digital learning resources will be made available to students in advance and the time they spend at the university will be used to work on assignments and group work. Self-study, activity, reflection and cooperation is a pre-condition for completion of the course.  

In order to be permitted to take the exam, the following must have been approved: 

• a minimum of 90 per cent attendance in laboratory teaching
• laboratory reports in accordance with specified criteria

Alle

Gradert skala A-F.

The course uses a blended learning approach, with a combination of attendance-based seminars and digital learning materials. Students will explore real-world cases emerging at the intersection of society, technology and their future profession.

English will be the primary language of communication.

None

All aids are permitted, as long as the rules for source referencing are followed.