BIOB1100 Chemistry - The Basis for Biomedical Analysis Course description

• Passed first year or equivalent of the Bachelor’s Programme in Biomedical Laboratory Sciences, or;
• Admitted to the Complementary Education in Biomedical Laboratory Science;

After completing the course, the student is expected to have achieved the following learning outcomes defined in terms of knowledge, skills and general competence:;

Knowledge;

The student;

• can describe the important properties of some of the most prevalent forms of human pathogenic microorganisms;
• can give examples of how microorganisms can cause disease
• can describe the main principles of antibiotics’ mechanisms of action
• can describe some of the resistance mechanisms of bacteria and explain how bacteria can develop resistance to an antibiotic
• can explain how microorganisms can be determined with the help of microscopy, cultivation, bio-chemical, immunological and gene technology methods and mass spectrometry, and describe the methods’ areas of use, possibilities and limitations
• can assess the importance that findings of different microorganisms can have in different types of sample material
• can explain the principles behind different immunological methods for detection of antibodies against microorganisms and describe the methods’ areas of use, possibilities and limitations;
• can explain quality assurance for relevant methods and analyses
• has knowledge of sample collection and the correct treatment of different types of sample material for microbiological investigations, and how analytical, pre- and postanalytical conditions influence analysis results
• can explain principles for sterilisation and disinfection
• is familiar with how social conditions affect the extent of various infectious diseases and the development of resistance at a national and global scale

Skills;

The student

• can detect, isolate and identify important human pathogenic microorganisms and carry out resistance testing on antibiotics, quality assuring methods used and assess sources of error
• can carry out and quality assure different methods for detecting antibodies in patients in connection with infection or vaccination and assess possible sources of error related to these
• can perform work in a responsible manner that safeguards infection control
• can follow procedures for responsible waste management both with regards to the danger of infection and the environment

General competence

The student

• is familiar with the laws and regulations relating to infection control in society and the health services
• can reflect on his/her own practice, keeping up with the latest academic research, seeking and receiving supervision
• can interpret an order containing clinical information and provide the correct test result

After completing the course, the student is expected to have achieved the following learning outcomes defined in terms of knowledge, skills and general competence:

Knowledge

The student

• can explain the structure of atoms and how the properties of the elements are decided by electron configurations
• can explain the chemical structure of molecules, ions and metals by looking at the most important types of chemical bonding
• can explain the reactivity of substances based on thermodynamic and kinetic principles
• can explain the classification of substances in organic chemistry and how the different substances react
• can explain the chemical and physical principles behind key chemical analysis methods
• can explain basic terms in measurement uncertainty

Skills

The student

• can convert units of measurement relating to mass, volume, temperature, amount and concentration of substances
• can name molecules and ionic bonds
• can conduct fundamental stoichiometric calculations and equilibrium calculations in chemical reactions
• can make the necessary calculations to create solutions with the desirable concentration
• has fundamental skills in practical laboratory work, including the correct use of weights and volumetric equipment
• can create control charts (Shewhart charts) and assess control results

General competence

The student

• can identify the connection between fundamental chemistry and biomedical analysis methods
• can describe safety procedures and handling chemicals in a responsible manner

The course consists of the following subject areas, specified below as the number of credits:

• General chemistry: 7.5 credits
• Chemical analysis principles: 2 credits
• Quality assurance: 0.5 credits

Combined assessment:

Part 1) Individual practical exam, 3 hours.

Part 2) Supervised individual written exam, 2 hours.

One overall grade is awarded based on the following weighting of the parts of the exam: Part 1, practical exam, 70 per cent; part 2, written exam, 30 per cent. Students must be awarded a pass grade A-E for both parts of the exam in order for a student to pass the course.

Resit exam: If the student is awarded an F in one part of the exam, this part of the exam must be retaken.

Students can appeal the grade awarded for part 2 of the exam.

No aids are permitted.

A-F.

Part 1, practical exam: One external and one internal examiner.

Part 2, written exam: All exam papers are assessed by two examiners. At least 20% of the exam papers will be assessed by an external examiner. The external examiner’s assessment shall benefit all students.

The course consists of the following subject areas, specified below as the number of credits:

• Microbiology, 7 credits
• Infection immunology, 3 credits

7 credits overlap with the course BIO2200 Medical Microbiology and Immunological Diagnostics

7 credits overlap with the course BIO1100 Fundamentals of Biomedical: Analysis - Chemistry, Analytical Techniques and Statistics